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Identifying symptomatic and asymptomatic carriers of SARS-CoV-2 is crucial in order to provide insights into the dynamics of the pandemic and implement effective measures to halt the spread of COVID Positive cases will be differentiated into symptomatic and asymptomatic, Luxembourg phone sex asymptomatic carriers will be followed up longitudinally together with COVID free individuals. The analyses will initially be carried out on collected blood samples and nasopharyngeal swabs, and subsequently extended to other sample types.

The symptom severity of COVID can vary tremendously from patient to patient: while some people do not show any or only very mild symptoms, others show severe or even life-threatening respiratory problems. The main objective of this study is to identify clinical, epidemiological age, sex, etc.

In addition, study participants will be followed over the course of up to one year to assess health consequences of COVID Studying patients in detail over a longer period of time will also allow the researchers to describe the evolution of symptoms over time disease trajectories after being positively diagnosed with COVID In order to ease remote monitoring of COVID patients, the researchers aim to identify vocal biomarkers associated with respiratory syndromes, fatigue, anxiety or emotions related to COVID Usually, the development of a drug generally takes several years.

The Luxembourg Institute of Health coordinates the implementation of this clinical trial protocol in Luxembourg. The objective of this interventional clinical trial is to evaluate the efficacy and safety of four experimental therapeutic strategies which, in light of the latest scientific information, might be effective against COVID To this end, the researchers compare patients that have received one of the following 5 modalities of care:.

While remdesivir as well as lopinavir and ritonavir are antiviral drugs that have been developed against Ebola virus and HIV infections, respectively; hydroxy-chloroquine is used against Malaria.

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Allocation of patients to the various treatment modalities will be randomized, i. This is called an open trial. The analysis of treatment efficacy and safety will be evaluated 15 days after inclusion of each patient.

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Self-administration of any of these drugs is strictly discouraged and could lead to severe side effects! This involves the provision of equipment and manpower as needed as well as help procure necessary reagents.

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Another important aspect is the development of an in-house test based on generic reagents in order to be able to extend the testing capacity, or to be able to test when other laboratories are running out of Luxembourg phone sex tests or when the virus undergoes mutations which can no longer be detected with commercial tests.

The second aim of the work package is the validation and testing of serological and virus-neutralizing immunoassays for detecting effective antibody responses against SARS-CoV-2 in patients and in the Luxembourg population. An own pipeline of SARS-CoV-2 protein antigen expression to be used for immunoassays will be built up, which will allow to remain independent even in a situation where external suppliers would not be able to deliver reagents anymore to Luxembourg. Together, the PCR-based and the immunoassay diagnostic approach will help develop a cohesive strategy for comprehensive SARS-CoV-2 testing in Luxembourg, which will be needed once the first wave of the pandemic crisis has ebbed down to guide the Luxembourg phone sex decision-makers on when and where public and economic life can be re-opened.

In this work package, a multidisciplinary team including healthcare professionals, a data scientist, epidemiologists and developers will identify potential eHealth solutions that may be used in the context of the pandemic and evaluate them according to their potential impact and complexity of implementation. Promising solutions will be presented to the crisis cell of the Ministry of Health. It is currently being piloted before an official launch. Another topic of importance will be an eHealth solution to support infection control during the post confinement phase.

The goal of this work package is to coordinate approaches for COVID statistical projections and their potential support for the healthcare system. Based on data provided by the Ministries, the team has developed a workflow for daily simulations on evolution, impact and spread of the COVID outbreak. For this workflow the researchers will agree on a model, identify relevant datasets and establish a review process before transmission to Ministries. In the short-term, such modelling projections will inform on the development of the COVID pandemic in Luxembourg and can forecast the burden on the healthcare system.

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In addition, the researchers are also working on mid-term projections to understand for how long social distancing and other measures need to be in place before people can safely their everyday life outside their homes. These patterns can be related to environmental attributes such as building density, greenness, shopping and leisure activities.

Also, the presence of the coronavirus can be linked to spatial data on health disorders collaboration with LIH, UL. The Ministry of Higher Education and Research and the Ministry of Health have revised the regulatory framework to enable the deployment of the latter. This to support them and direct their proposals to the other work packages put in place by the Task Force to obtain scientific assessment of the proposals and provide relevant feed-back to companies.

The second aim is to call on companies to submit ideas and proposals via this channel to the scientific WPs. And finally, the third aim is to provide the scientific health community with the Luxembourg phone sex to call for potential solutions and services from companies via this channel. The overall goal of this work package is to develop an aligned communication strategy on COVID within the Research Luxembourg context. This work package supports the task force in its communication efforts, coordinates the press requests and develops actions to disseminate the relevant information to the appropriate audience.

The working group will streamline the communication among the institutions and synchronize the various institutional communication channels to get the most efficient spreading of information.

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The team supports healthcare communities by identifying and actively suggesting solutions that can be implemented to cope with the current Coronavirus crisis. This may involve practical questions, such as how to respond to expected shortages, but also scientific and medical issues that need to be addressed.

The team also responds to requests from the government and other implicated stakeholders and prepares strategic decisions. Finally, the work package supports the scientific and healthcare community in keeping up to date with the rapidly evolving state of knowledge on SARS-Cov-2 and COVID by screening the latest literature and setting up a selected scientific literature feed.

This work package aims to implement four main initiatives to boost research and collaborations, and mobilise funding from different sources. Specifically, the first initiative consists in the set-up of a centralised national COVID platform to coordinate new research projects, which could subsequently be eligible for funding by the FNR through a dedicated fast-track call for proposals. This website will support the research community, facilitate exchange, communication and collaborations and foster the creation of synergies.

Through its different modules, the platform allows researchers to submit project ideas, browse ongoing projects and submitted proposals, as well as share and discuss new concepts. The second initiative of the work package aims to network with other research funders and contribute to international research programmes and initiatives. The third action seeks to channel funding and contributions from other foundations and private donors, while the fourth action aims to provide discretionary FNR funding for urgent and important research projects upon recommendation by the Task Force.

Flows of goods and services are at the core of how economic prosperity is created. During the COVID pandemic, these flows have been dramatically impacted and altered, while necessitating Luxembourg phone sex ones. Accordingly, this work package operates along three pillars:. Coordinate the provision of support from the national research community to healthcare providers and the government in order to contain the current COVID pandemic. Help identify and centralise a variety of priority activities, leveraging on the cross-sectoral expertise in biology, medicine, mathematics, computer science, Luxembourg phone sex, economics and social science.

Be the point of contact between the national research ecosystem, the clinical community and the authorities to foster common projects. Statistical simulations on the evolution, impact and spread of the COVID pandemic to provide short- and medium-term projections and thus facilitate decision-making on when restrictions could be lifted. Work packages. To this end, the researchers compare patients that have received one of the following 5 modalities of care: standard of care standard of care plus remdesivir standard of care plus lopinavir and ritonavir standard of care plus lopinavir, ritonavir and interferon beta standard of care plus hydroxy-chloroquine While remdesivir as well as lopinavir and ritonavir are antiviral drugs that have been developed against Ebola virus and HIV infections, respectively; hydroxy-chloroquine is used against Malaria.

WP Luxembourg phone sex solutions for hospitalised and ambulatory patients Team leader: Damien Dietrich HRS In this work package, a multidisciplinary team including healthcare professionals, a data scientist, epidemiologists and developers will identify potential eHealth solutions that may be used in the context of the pandemic and evaluate them according to their potential impact and complexity of implementation.

Also, the presence of the coronavirus can be linked to spatial data on health disorders collaboration with LIH, UL ; — to assess the medium- and long-term macroeconomic impact of the health crisis and the resulting lockdown measure going beyond the OECD study on wealth, wealth inequalities and welfare deterioration, and evaluate their distributional effects in relationship with digital isolation, household vulnerability, unemployment, housing burden collaboration with UL ; — to review the discussions around and advise on the appropriate macroeconomic policy responses collaboration with UL ; — to assess the impact of the substitution of physical activities e.

WP Ideas for new initiatives in the pandemic context Team leader: Marc Schiltz FNR This work package aims to implement four main initiatives to boost research and collaborations, and mobilise funding from different sources. Accordingly, this work package operates along three pillars: Assessment of the impact on the different logistics providers in Luxembourg. In the course of this, input from an online survey supported by INCERT will feed data to a dashboard that will provide information on the changing logistics environment.

Analysis of supply chains that support various sectors of the economy in Luxembourg. A report will feature various supply chains considerations and will be a valuable input for the exit strategy WP An online survey is envisioned as well. To that end, WP13 will support WP04 in the planning process of this major operation. Sorry, your blog cannot share posts by .

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